PRESENCE OF LOWER TEMPERATURE-DEPENDENT ANTIBODY WITH LOW AVIDITY TO C100-3 (HCV) ANTIGEN IN VOLUNTARY BLOOD DONORS
نویسندگان
چکیده
منابع مشابه
Presence of lower temperature-dependent antibody with low avidity to C100-3 (HCV) antigen in voluntary blood donors.
Serum samples with lower temperature-dependent antibody with low avidity to C100-3 (HCV) antigen were found in 0.19% of 23,197 voluntary blood donors at this blood center. They showed positive C100-3 antibody activity at 24 C but not at 37 C. The antibody activity bound to C100-3 antigen at lower temperature disappeared after incubation for 60 min at 37 C or treatment with 8 M urea. Other marke...
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We tested serum samples from blood donors by using first-, second-, and third-generation enzyme immunoassays or recombinant immunoblot assays. Second- and third-generation assays gave comparable results. Circulating hepatitis C virus RNA was found in a high proportion of reactive samples. A lack of reactivity or low-level reactivity predicted the absence of hepatitis C virus RNA in 100% of the ...
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Objective Third generation anti-HCV ELISA is currently recommended for the diagnosis of HCV infection. We determined its specificity in voluntary blood donors (VBDs) and patients with chronic liver disease (CLD) in relation to confirmatory line immunoassay (LIA) and reverse transcription polymerase chain reaction (RT-PCR). Material and Methods: 1926 serum samples of VBDs and 16 HCV related CLD ...
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Objective Third generation anti-HCV ELISA is currently recommended for the diagnosis of HCV infection. We determined its specificity in voluntary blood donors (VBDs) and patients with chronic liver disease (CLD) in relation to confirmatory line immunoassay (LIA) and reverse transcription polymerase chain reaction (RT-PCR). Material and Methods: 1926 serum samples of VBDs and 16 HCV related CLD ...
متن کاملDetection of hepatitis C virus (HCV) core-specific antibody suggests occult HCV infection among blood donors.
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ژورنال
عنوان ژورنال: Japanese Journal of Medical Science and Biology
سال: 1992
ISSN: 0021-5112,1884-2828
DOI: 10.7883/yoken1952.45.1